Biolarvicide

BACTIVEC® is a biolarvicide that has been widely used for the biological control of different mosquito species acting as vectors for a number of tropical diseases. It is highly efficient, and no adverse events in man or the accompanying flora and fauna have been reported after its use.

This product is formulated as a gray-colored aqueous suspension that is easily dispersed into the water of mosquito breeding sites. It is not flammable or corrosive.

It has been employed as agricultural pesticide, to kill larvae in breeding sites of disparate ecological characteristics such as puddles, lagoons, ponds, salt marshes, wetlands, swamps, flooded rice fields, irrigation and draining channels, small streams, rivers, flooded pastures and watering holes.

It acts with proved effectiveness on mosquitos' larvae of Aedes, Culex, Anopheles, Mansonia, Psorophora and black fly species, between the first and the third phase of their lives, showing high mortality rates after 24 to 48 hours of application. Effective for the control of dengue, malaria, filariasis, encephalitis, and other mosquito transmitted diseases. It comes in 30 ml, 1 L and 20 L plastic bottles. The Business Group, LABIOFAM offers an effective biological regulating product, BACTIVEC, made up mainly by endotoxic spores and crystals of the Bacillus thuringiensis SH-14 bacteria, free in its natural status, and by other essential elements.
BACTIVEC tackles mosquitos' larvae and black flies through the action of the bacteria that form the product. It is ingested and paralyzes the larvae's intestinal walls from 24 to 48 hours after ingestion. High temperatures favor the larval activity and, subsequently, BACTIVEC´s quick action.

Chemical physical properties
Active ingredient: Bacillus thuringiensis SH-14
Type of formulation: Aqueous suspension
Presentation: Grey liquid
Density: 1.0-1.5
Boiling temperature: 100 Degrees centigrade.
Freezing point: 0 Degree centigrade.
Solubility: Water-soluble
Shelf life: 2 years
Toxicology: Slightly toxic

This biolarvicide is sprinkled, both by air and land spraying, on the surface of breeding sites. The first method is recommended for areas over one hectare and all types of manual sprinkler can be used for the second method.
The product may be stored in cool, dry and shady places between 4 and 30 Degrees centigrade.
The dose to apply will depend on the surface area and not on the depth, analyzing factors like: the larvae phase, mosquito's abundance and the quality of water in breeding sites. It is shown in the table below.

Biolarvicide

GRISELESF® is a biolarvicide that has been widely used for the biological control of different mosquito species that act as vectors for a number of tropical diseases. It is highly efficient, and its innocuity towards man or the accompanying flora and fauna has been demonstrated both by safety studies and the absence of adverse event reports arising from its use.

This product is formulated as a gray-colored aqueous suspension that is easily dispersed into the water of mosquito breeding sites. It is not flammable or corrosive.

GRISELESF® is a biodegradable product characterized by its effective, long-lasting action, flexible storage conditions and ease of application.

This biolarvicide acts on mosquito larvae between their first and third developmental stages. It produces excellent results on species from the genera Culex, Anopheles, Mansonia and Psorophora.

LABIOFAM Business Group offers an effective biological regulating product which is made up by endotoxic spores and crystals of the Bacillus sphaericus 2362 bacteria and other essential elements for the mosquitoes and larvae control. GRISELESF is an ingestion-biolarvicide that causes intestinal paralysis and poisoning due to the action of endotoxic spores and crystals, which lead to bacterial germination and growth in the larval intestine followed by the formation of new spores which are released once the carcass in disintegrated.

One of the advantages of this product lies on its property of remaining active in the environment for a period from 3 to 6 months depending on the type of breeding site and species to control. It can also expand its action due to the bacillus multiplication on dead larvae. This turns the product into a very inexpensive bioplaguicide which is applied by air or land spraying. The first method is recommended for areas over one hectare and all types of manual sprinkler can be used for the second method.

Physical and chemical properties

Active ingredient: Bacillus sphaericus stump 2362

Type of formulation: Aqueous suspension

Presentation: Grey liquid

Density: 1.0-1.5

Boiling point: 100 Degrees centigrade

Freezing point: 0 Degree centigrade

Solubility: Water-soluble

Shelf life: 2 years

Toxicology: Slightly toxic

It is not compatible with plaguicides formulations whose active principle is the product commonly known as Temephos (Abate) and other commercial names, nor for breeding sites with PH higher than 8.5. It is very effective and a strong action has been reported in species like Culex quinquefasciatus, Anopheles albimanus, Anopheles darlingi, Anopheles nuñeztovari, Anopheles gambiae (malaria vectors), Aedes taeniorhynchus (mosquito of the coast, which transmits encephalitis), Uranotaenia saphirina, Psorophora confinnis and Mansonia Sp. After some years of application no resistance by the mentioned species to the product has been detected, nor harm to man or nature in general.

Easy to store: no high technology required, it is enough to keep it in cool, dry and shady places at temperatures under 30 degrees centigrade. The product comes on 4 and 20 litter- plastic bottles.

Vector Control

Bactivec® & Griselesf®. Common way in vectorial control

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One of the main problems faced by the control of tropical-disease-transmitter vectors is the indiscriminate use of chemical insecticides, which have caused the appearance and propagation of resistance (World Health Organization, 1992). For two decades, 54 species of Anopheles mosquito have been reported as resistant to DDT, 28 to organ-phosphoric and 19 to carbamates and piretroids. This number is presently larger.

The irrational and excessive use of chemicals, their high toxicity and a lengthy permanence in the environment affects ecosystems and the human life. These are the reasons why, alternative methods have been searched in recent years, such as the biological combat.

Among the biological methods, the use of sporogenic bacteria has been recommended by the World Health Organization (WHO) to contribute to the non affectation of environment, as they are innocuous for men and fauna, easy to apply, low cost and highly effective against larva of culicidus and simulidus, casual agents’ vectors of diseases such as malaria, dengue and onco-cercosis, among others.

Taking researches carried out as precedent, LABIOFAM Business Group develops two bio-larvicides which contain bacteria Bacillus sphaericus 2362 strain in Griselesf® and Bacillus thuringiensis, israelensis variety, in Bactivec®. Both products work on Anopheles, Culex, Mansonia and Psorophora mosquito larva, and some species of aedes and simulidus, without affecting human health or beneficial organisms such as fishes and other hydrobionts.

Grisel Montero Lago, PhD in Biologic Sciences, who works as specialist at LABIOFAM’s Branch of Vector Biologic Control in the Cuban capital, developed the technology to produce these bio-larvicides as part of a project sponsored by the WHO.

Griselesf® stays in the environment for a period of 3 to 6 months, depending on the bio-ecological characteristics of breeders, while the bio-larvicide responds to Bactivec® trademark, made up of spores and endotoxic crystals, it counts on a formulation characterized by having quick action, between 24 and 48 hours after applied. That behavior makes it valuable for emergency situations.

 “The operational use of these bio-larvicides, with probed effectiveness in antivectorial fight— the Doctor refers— has allowed them to be registered in several countries on Asia, Africa and Latin America.”

African students invent groundbreaking anti-malaria soap, win $25,000 GSVC award (VIDEO)

Home / Health / African students invent groundbreaking anti-malaria soap, win $25,000 GSVC award (VIDEO)

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Two African students have created a malaria-repellant soap using local herbs, and have won, consequently, a $25,000 Global Social Venture Competition (GSVC) award.

Moctar Dembélé who hails from Burukina Faso and Gérard Niyondiko, from Burundi, are the first non American born/citizen, to win the Global Social Venture Competition.

Both are students of the Intsitut International de l’Eau et de l’Envirronement de Ouagadougou (International Institute of water and environment), in Burkina Faso.

The invention will carry the name Faso soap.

“The soap will be available first here, and then given to NGO”, Gerard Niyondiko, Technical Manager of Faso soap said in a video that was posted online on Monday.

The soap is made from karate citronella, and other herbs that are still a secret.

“We want a simple solution, because every one uses soaps, even in the very poor communities”, Moktar Dembélé, General Manager of Faso soap said.

In Africa, the most dangerous is mosquito that is the only cause of malaria. 300 million of cases of Malaria each year are reported in Africa, especially in sub Sahara where 90% cases are and still the main cause of death, according to the explanation of the introduction video.

Faso soap becomes then a solution from Africa to African problems as it requires nothing, even mindset change or big economic efforts.

The GSVC is the only international competition of Social Business Plans, dedicated to students, young graduates, and entrepreneurs with high social and/or environmental start-ups.

More information on GSVC Facebook page.

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Mali pilots ‘insectary-in-a-box’

December 13, 2012

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Top view of the insectary-in-a-box, which was created from a shipping container. Credit: Elie Bankineza.

In March 2012, three months before the AIRS project had planned to begin annual indoor residual spraying (IRS)—an intervention that protects millions of people from malaria—Malian soldiers overthrew the central government. As a result of the coup, AIRS had to carry out IRS work independent of their previously established government partners including entomological monitoring, a crucial activity that assesses if insecticide kills malaria transmitting mosquitoes. AIRS had less than one month to build an insectary where they could rear mosquitoes and test insecticide in time for the IRS campaign. The team developed an innovative solution to this predicament—they converted a 40 foot x 8 foot shipping container into the first ever insectary-in-a-box.

This mini, mobile insectary was placed in the AIRS compound in Bamako. The container was purchased locally and converted into an insectary for less than US$20,000. It was operational in a mere three weeks. By creating the insectary-in-a-box, AIRS did not have to construct or renovate a building, a process which can be costly, time consuming, and bureaucratic.

The insectary is divided into three rooms: one for keeping adult mosquitoes, one for rearing mosquitoes from larvae, and one for completing morphological identification, dissection, and susceptibility testing. (See figure below.) The insectary is outfitted with air conditioners and humidifiers to keep adult mosquitoes at optimum conditions.

“I personally visited the insectary and I was very impressed with the division of the rooms. I was also impressed to find a Malian entomologist who really had the know-how and who has backup from the AIRS headquarters staff,” said Jules Mihigo, resident advisor for President’s Malaria Initiative. To ensure that mosquitoes do not escape when entomologists are coming and going, Mr. Mihigo had the idea to add double doors to the insectary entrance.

To test the insecticide, AIRS Mali entomologists collected mosquito larvae from sites that were slated for IRS and brought them to the insectary-in-a-box. The team exposed mosquitoes to bendiocarb insecticide and found the average mortality rate for the mosquitoes was approximately 97 percent. This data helped program managers to confirm that bendiocarb insecticide was effective at killing vector mosquitoes. Entomologists may also take mosquitoes reared in the insectary to field sites to complete further testing.

“The AIRS insectary and the entomological monitoring work allowed the team to make critical decisions and in a timely manner to improve the quality of IRS in Mali,” said AIRS Mali entomology coordinator Moussa Cissé, who helped develop the insectary.

Entomologist inside the insectary-in-a-box. Credit: AIRS.

While the insectary-in-a-box was originally developed in response to a crisis, the insectary can be used for several years. “Months after its establishment, a good density of mosquitoes are reared and maintained in the insectary, which means this is an optimum environment for rearing mosquitoes,” said Dereje Dengela, AIRS technical director. Since the insectary in-a-box is mobile, it could be lifted and relocated so that another project or organization could sustain the insectary after the AIRS project ends.

IRS implementers from other countries are already buzzing about recreating the insectary in-a-box model, which was recently presented at the American Society for Hygiene and Tropical Medicine. “I discussed the Mali experience with many national malaria control program directors and many are ready to follow it,” said Mr. Mihigo. “For the country which does not have an insectary, I strongly recommend the insectary in-a-box so that they can have a place where they can perform entomological monitoring.” The AIRS team is considering developing similar insectaries in Angola and Liberia in 2013.

Thanks to their creative thinking, the AIRS team developed a quick, cost-effective solution to carry out entomological monitoring that improves the quality of IRS. During the IRS campaign, which ran from July 23 to September 6, AIRS sprayed 206,295 structures with insecticide (99 percent of the target) and protected 762,146 people from malaria, including 18,561 pregnant women and 145,953 children under five.

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Tags: entomological monitoring, insectary, Mali

ECOWAS, PARTNERS TAKE BOLD STEP TO ELIMINATE MALARIA

ECOWAS, PARTNERS TAKE BOLD STEP TO ELIMINATE MALARIA

ABUJA, Nigeria, April 15, 2013/African Press Organization (APO)/ — ECOWAS and its partners have achieved another milestone in their stride towards the elimination of malaria in the region with the ground breaking ceremony for the construction of a biolarvicides factory in Port Harcourt, capital of Nigeria’s south eastern Rivers State.

The President of the ECOWAS Commission His Excellency Kadré Désiré Ouédraogo and Nigeria’s Minister of Health Prof. Onyebuchi Chukwu, who represented President His Excellency Dr. Goodluck Jonathan, unveiled the plaque at a well-attended ceremony on Thursday 11th April 2013.

The Nigerian factory is one of the three being built in three ECOWAS Member States under a Tripartite Agreement between ECOWAS, Cuba and Venezuela for the production of boilarvicides, a safe substance that kills the larvae of malaria vectors, mosquitoes. The two other factories are earmarked for Cote d’Ivoire and Ghana under the campaign which seeks to eliminate malaria in the region by 2015.

Under the campaign, ECOWAS seeks to strengthen the vector control component of the intervention to rid West Africa of malaria, which is a major public health problem that also stunts the economic development of the region and Africa as a whole.

The ground breaking ceremony was preceded by a Town Hall Meeting at the packed 5,000-capacity Diete Spiff Civic Centre, Port Harcourt, where representatives of civil society organizations, religious and traditional rulers, women and youth groups and ECOWAS Commission officials, among others, discussed the ramifications of malaria vector control intervention, which the World Health Organization (WHO) has acknowledged as the only strategy that can reduce malaria transmission from high level to zero.

During the session, a panel of experts headed by Dr. Chioma Amajoh, the immediate past National Coordinator of Nigeria’s Malaria Control Programme, fielded questions from the audience. Dr. Amajoh, nicknamed “Mama Malaria” for her sustained anti-malaria efforts, underscored the need for all stakeholders – governments, Non-governmental organizations, the private sector and the citizens to play their role to make the regional campaign a huge success.

Addressing the gathering, President Ouédraogo reaffirmed ECOWAS’ commitment and determination to eliminate the malaria scourge so as to free resources for the economic development and to enable the region attain its full potentials.

The Organization’s major priorities of peace and security coupled with economic development cannot be achieved unless such threats as malaria are effectively addressed, he added.

The president commended development partners especially the governments of Cuba and Venezuela for supporting the ECOWAS campaign, noting that all hands should be on deck until the war against malaria is won. He also expressed confidence in the prospect of achieving the 2015 date for malaria elimination, while expressing the Commission’s appreciation to the government and people of Rivers State and especially Governor Rotimi Chibuike Amaechi, one of Nigeria’s two Malaria Ambassadors for partnering with ECOWAS on the anti-malaria initiative.

In an address on behalf of President Jonathan, Health Minister Prof. Chukwu thanked ECOWAS leaders for initiating the Campaign with the two Latin American countries providing both financial and technology transfer support.

He listed the Federal Government’s various malaria initiatives and highlighted the need to strengthen indoor residual spraying of mosquitoes as well as environmental sanitation through the reintroduction of sanitary health inspectors in the country.

Governor Chibuike reaffirmed Rivers State’s total support to the regional campaign and promised that the government would do all that is required to ensure that the state maintained its lead in the national malaria elimination campaign.

Speaking in the same vein, the State Commissioner for Health Dr. Tamunoiyoriari Sampson Parker described the ceremony as “a paradigm shift and historic event for us as it marks the build up of efforts to achieving the Millennium Development Goals and eventual target of zero-incidence in locally contracted malaria”

There were also goodwill messages from the WHO and Nigeria’s Minister of Defence, represented by Dr. Uzor Chima, who expressed the hope that the proposed involvement of military personnel would provide the regional campaign with the discipline and precision needed for its successful prosecution.

Dr. Adhiambo Odaga, Managing Director of Dangote Foundation, who represented business mogul, Alhaji Aliko Dangote, another Malaria Ambassador and head of the Dangote Group, pledged the Group’s support to the regional anti-malaria initiative and stressed the need for public-private sector collaboration.

The Cuban envoy to Nigeria, Ambassador Milanes Ramos Hugo, who attended the two events with his wife, reiterated his country’s total commitment and support to the ECOWAS campaign as a demonstration of South-South cooperation.

In his vote of thanks, the Vice President of the ECOWAS Commission, Dr. Toga Gayewea McIntosh thanked the partner countries, the Rivers State Government, the Local Organizing Committee and Governor Amaechi in particular, for lending their full support to the ECOWAS campaign, which is in furtherance of the ECOWAS of people agenda and the goal of regional development and integration.

The ECOWAS Heath Adviser, Dr. Mariane Ngoulla appealed to all stakeholders to be effective in their roles, adding that instead of being “mosquito farmers” necessary measures should be taken to stop the indiscriminate breeding of the malaria vector.

The ECOWAS delegation to the twin-event included Mr. Sunny Ugoh, the Director of Communication and Dr. Johnson Buanuh, Director of Environment, who explained that studies by the Commission have shown that the biolarvicides for the campaign are safe. The Private Sector Director, Mr. Alfred Braimah, also explained that apart from producing the substance for malaria elimination, the three factories will also create jobs in the region.

SOURCE 

Economic Community Of West African States (ECOWAS)